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Why pass box?

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Why pass box?

A pass box, also known as a pass-through box or transfer hatch, is a specialized piece of equipment used in various industries and environments, such as cleanrooms, laboratories, pharmaceutical manufacturing, and food processing. The primary purpose of a pass box is to facilitate the controlled transfer of materials or items between two separate environments without compromising the cleanliness or integrity of either side. Here are some key purposes and features of a pass box:

  1. Contamination Control: Pass boxes are critical in maintaining a controlled and sterile environment. They prevent the introduction of contaminants, such as dust, particles, microbes, or other pollutants, from one area to another. By minimizing the risk of cross-contamination, they are essential in settings where cleanliness is crucial, such as pharmaceutical production, research laboratories, and semiconductor manufacturing.
  2. Controlled Access: These boxes provide a means for personnel to transfer items or materials into or out of restricted or controlled environments, like cleanrooms, without having to enter those environments themselves. This helps ensure that only sanitized or authorized items are introduced into the clean area, thereby maintaining the environmental integrity.
  3. Safety: Pass-through boxes enhance safety by reducing the need for personnel to move in and out of hazardous areas, such as radioactive or biohazardous environments. This limits the risk of exposure to dangerous substances and reduces the potential for accidents.
  4. Material Protection: During the transfer process, pass boxes protect sensitive materials or samples from exposure to external elements like temperature fluctuations, humidity, or air contamination. This is especially important for materials that are sensitive to environmental changes, such as certain chemicals, biological samples, or electronic components.
  5. Efficiency: By eliminating the need for personnel to exit a controlled environment to retrieve or store items, pass boxes improve workflow efficiency. This can save time, reduce disruptions, and increase productivity in operations.
  6. Security: Pass boxes can be equipped with locks, security features, or access control systems to ensure that only authorized individuals can use them. This is particularly important in high-security areas or in industries where the protection of intellectual property or sensitive materials is a priority.
  7. Compliance: In industries like pharmaceuticals, biotechnology, and food processing, pass boxes help companies comply with regulatory requirements and Good Manufacturing Practices (GMP). They provide a controlled method for material transfer that can be documented and validated, ensuring adherence to industry standards.
man using microscope

Pass boxes come in various types, including standard pass boxes, air shower pass boxes (equipped with air jets to remove particles), and pass boxes with HEPA or ULPA filters for air purification. The specific purpose and features of a pass box can vary depending on the intended application and the level of cleanliness or control required in the environments it serves. For example, an air shower pass box might be used in semiconductor manufacturing to remove particles from items before they enter the cleanroom, while a pass box with HEPA filters might be more appropriate for a pharmaceutical lab where air purity is paramount.

Overall, pass boxes are a vital component in maintaining controlled environments in various industries, ensuring both the safety of personnel and the integrity of the materials or products being handled.


  1. What is a pass box and how is it used? A pass box, also known as a pass-through box or transfer hatch, is a specialized containment unit used in controlled environments like cleanrooms, laboratories, and pharmaceutical manufacturing areas. Its primary function is to enable the transfer of materials between two different environments while maintaining the cleanliness and integrity of both. This helps prevent contamination and ensures a controlled exchange of items.
  2. What are the different types of pass boxes available? There are several types of pass boxes, each designed for specific requirements. The main types include standard pass boxes, which are basic models for simple transfer of items; air shower pass boxes, equipped with air jets to remove surface particles from items being transferred; and pass boxes with High Efficiency Particulate Air (HEPA) or Ultra Low Penetration Air (ULPA) filters, which are used for air purification to remove even finer particles.
  3. How do pass boxes help in contamination control? Pass boxes play a crucial role in contamination control by isolating the transfer of materials from one environment to another. This isolation prevents contaminants such as dust, particles, and microbes from entering clean areas. In industries where sterility and cleanliness are paramount, like pharmaceuticals and biotechnology, pass boxes are essential for maintaining a sterile environment.
  4. Can pass boxes be customized for specific needs? Yes, pass boxes can be customized to meet the specific requirements of different industries and applications. This customization can include size, material construction, type of filtration system (HEPA or ULPA filters), type of door mechanism (mechanical interlock or electronic interlock), and additional features like UV sterilization lights or air shower functionality.
  5. What are the maintenance and cleaning requirements for pass boxes? Regular maintenance and cleaning are vital for ensuring the effective operation of pass boxes. The frequency and method of cleaning depend on the specific use and industry standards. Generally, the interior and exterior surfaces of the pass box should be wiped down with appropriate disinfectants. HEPA or ULPA filters, if present, should be checked and replaced according to the manufacturer’s recommendations. Additionally, any mechanical parts, like interlocking doors, should be regularly inspected and maintained to ensure smooth operation.

Here’s a list of common types of pass boxes:

  1. Standard Pass Box (Static Pass Box): This is the most basic form of pass box, used for simple transfer of materials without additional air cleaning or purification features. It typically includes interlocked doors to prevent both doors from being opened simultaneously, thus maintaining cleanliness levels.
  2. Dynamic Pass Box: Dynamic pass boxes are equipped with a ventilation system that provides a continuous flow of filtered air (usually through HEPA filters). This helps to remove particulate contaminants from items placed in the box before they are transferred to the next environment.
  3. Air Shower Pass Box: These pass boxes include an air shower feature that blasts high-velocity, clean air onto items to dislodge and remove surface particles. They are especially useful in environments where minimal contamination is critical, such as semiconductor manufacturing or precision engineering facilities.
  4. Laminar Air Flow Pass Box: Laminar flow pass boxes provide a continuous flow of unidirectional, HEPA-filtered air. This design is intended to create a particle-free working environment and is ideal for the protection of sensitive products or processes.
  5. HEPA/ULPA Filtered Pass Box: These pass boxes are equipped with High Efficiency Particulate Air (HEPA) or Ultra Low Penetration Air (ULPA) filters for advanced air purification. They are used in environments where extremely high levels of air cleanliness are required.
  6. Fire-Rated Pass Box: Designed for use in environments where fire safety is a concern, fire-rated pass boxes are constructed with materials that can withstand high temperatures and help prevent the spread of fire.
  7. Stainless Steel Pass Box: Made entirely of stainless steel, these pass boxes are durable, easy to clean, and resistant to corrosion. They are commonly used in pharmaceutical, medical, and food processing environments.
  8. Floor-Mounted/Walk-Through Pass Box: Larger than standard pass boxes, these are designed to allow transfer of bigger items or even for personnel to walk through while maintaining environmental control. They are often used in settings where larger equipment or materials need to be moved between controlled environments.


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