01. Bag In Bag Out – BIBO

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01. Bag In Bag Out – BIBO

What is the bag-in-bag-out?

Bag-in-Bag-Out (BIBO) is a method used for safe and secure replacement of contaminated hazardous filters, particularly High-Efficiency Particulate Air (HEPA) filters, in environments where air cleanliness. The BIBO system allows for the filters to be safely changed without exposing personnel or the environment to the contaminants captured by the filter.

YOUTH's BIBO schematic
YOUTH's BIBO schematic

Variations of BIBO Filter Replacement Procedures

bag in bag out system working diagram
Standard BIBO Project Sample

The Bag-in-Bag-Out (BIBO) procedure, primarily associated with the replacement of air filters in situations where the filter contains hazardous contaminants, can vary slightly depending on the industry and specific use case.
Some variations of the BIBO process might include:

  • Single Bag BIBO:
    The simplest form is where a single bag is used to enclose and remove the contaminated filter from its housing. This method is typically used when the level of containment required is less stringent.
  • Double Bag BIBO:
    A more secure method that involves a second containment layer. The contaminated filter is first placed in one bag, which is then placed inside a second bag, adding an extra level of protection against potential exposure.
  • Multiple Bag BIBO:
    For environments with extremely hazardous materials, multiple bags may be used to ensure the highest levels of containment. Each additional bag provides an extra level of security.
  • Safety Cabinet BIBO:
    This variation includes a safety cabinet or a safe-change housing. The filter is changed inside a containment cabinet with its own built-in BIBO system, further minimizing the risk of exposure.
  • Custom BIBO Systems:
    For unique applications, custom BIBO systems are designed to fit specific requirements. These might include variations in bag materials, housing designs, and sealing mechanisms to address particular contaminants or to fit specialized equipment.
  • Portable BIBO Units:
    Some BIBO systems are designed to be portable, allowing them to be moved to the filter location. This makes them ideal for environments where filters may not be centrally located or easily accessible.
    The key aspect of all these types is the ability to safely and effectively isolate the contaminated filter from the surrounding environment and personnel during the change-out process.

Customized BIBO Housing and Unit Solutions

YOUTH is dedicated to providing superior air filtration solutions tailored to meet the diverse needs of our clients. We take pride in our specialized Bag-in-Bag-Out (BIBO) filter housing and unit production, offering a range of customized options designed for optimal contamination control and efficiency. Our bespoke BIBO systems include four distinct configurations:

Single High Efficiency (assembled from a single HEPA)
Single High Efficiency
(assembled from a single HEPA)
Medium Efficiency + High Efficiency (assembled from medium and HEPA filters)
Medium Efficiency + High Efficiency
(assembled from medium and HEPA filters)
Double High Efficiency (assembled from two HEPA filters)
Double High Efficiency
(assembled from two HEPA filters)
Double High Efficiency
(assembled from two HEPA filters)
  • Single High Efficiency: This unit is assembled using a single High-Efficiency Particulate Air (HEPA) filter, designed for environments requiring precision air filtration. It captures 99.97% of airborne particles, making it ideal for sensitive applications where clean air is paramount.
  • Medium Efficiency + High Efficiency: Combining a medium-efficiency pre-filter with a HEPA filter, this BIBO housing is engineered to extend the lifespan of the HEPA filter by capturing larger particles beforehand, thus enhancing overall filtration effectiveness and operational efficiency.
  • Double High Efficiency: Our double HEPA configuration is assembled with two consecutive HEPA filters. This setup provides an advanced level of air purification, significantly reducing the concentration of ultrafine contaminants, and is suited for the most demanding cleanroom conditions.
  • Medium Efficiency + Double High Efficiency: By integrating a medium efficiency pre-filter with two HEPA filters, this model delivers heightened levels of air cleanliness. The initial layer captures larger particulates, allowing the dual HEPA filters to effectively remove finer particles, thereby providing robust protection against a wide spectrum of contaminants.

YOUTH's Material & Key Parameters

Stand module has three airflow options 1700m³/h, 3400m³/h, and 4250m³/h. 

YOUTH bag in bag out Factory Processing 7
BIBO Production by YOUTH's Engineer
YOUTH bag in bag out Factory Processing 9
BIBO made by SS in YOUTH's Factory
  • Material Selection: Opt for premium 304 stainless steel or durable cold-rolled sheet metal to fabricate the equipment housing, providing robust durability and resistance to corrosion.
  • Construction Standards: Use materials with a minimum thickness of 2.0mm to ensure structural integrity and longevity of the equipment.
  • Welding Quality: Employ continuous welding techniques on all pressure-bearing joints and seams, eliminating any potential air gaps for airtight sealing.
  • Pressure Tolerance: Construct the housing to endure pressure differentials of up to ±2500pa, thereby ensuring safe operation under various environmental stressors.
  • Safety Assurance: Through meticulous construction and choice of high-grade materials, confirm that the equipment meets or exceeds industry safety standards for pressure resistance and air purity control.
Streamlined Linear Scanning Process:
BIBO Linear Scanning Process Modular
BIBO Linear Scanning Process Modular
  • Whole-section Scanning Approach: The method encompasses scanning the entire cross-section of the filter’s air outlet in a single, comprehensive motion, connecting seamlessly with an external scanning port.
  • Continuous Sampling Operation: Throughout the scanning procedure, the full sampling head remains active, ensuring consistent and thorough assessment.
  • Efficient Design Simplicity: The system’s straightforward architecture allows for rapid scanning, significantly reducing the duration of the process.
  • Market Prevalence: Due to its swift scanning capability and high efficiency, this linear scanning technique is favored and prevalent in commercial applications.
Sequential Row-by-Row Scanning Technique
BIBO Row-by-row scanning
YOUTH's BIBO Row-by-row scanning
  • Four-Head Sampling Strategy: This approach utilizes four distinct sampling heads, each aligning with one external scanning port to comprehensively assess the entire air outlet cross-section of the filter.
  • Alternating Active Sampling: During the scanning process, activation occurs sequentially—only one sampling head operates at a given time, while the remaining three standby, ensuring focused analysis.
  • Methodical Scanning Sequence: For instance, when the second sampling head is engaged, the first, third, and fourth heads remain inactive. This pattern continues, rotating through each sampling head to complete a full scan.
  • Intricate and Extended Duration: Although the process is more complex and time-intensive compared to other methods, it delivers high precision in its scanning results.

YOUTH BIBO Systems' Structural and Functional

BIBO Housing in YOUTH's Factory
Semi-Finished BIBO Housing in YOUTH's Factory
YOUTH bag in bag out Factory Processing 3
Finished BIBO Housing in YOUTH's Factory
  • Built to Withstand: The boxes are crafted by YOUTH to handle up to -2500Pa pressure for a duration of 60 minutes without any signs of damage or permanent alteration in form, in line with the demands of the exhaust device standard (JG/T497-2016).
  • Guaranteed Sealing: Each BIBO system showcases exceptional sealing capabilities, maintaining air tightness at high pressures of both +3600Pa and -3600Pa, compliant with the technical specifications of exhaust devices and client-specific criteria for air permeability.
  • Uniform Aerosol Levels: By generating dust upstream through reserved holes and employing a high-efficiency pre-filter, the aerosol concentration at nine strategically placed sampling points upstream deviates no more than ±20% from the average—ensuring uniformity that meets all pertinent standards.
  • Precise Leak Discovery: Engineered for accuracy, the systems can detect and locate artificial leakages fashioned on reference filters with a standard gauge stainless steel needle, fulfilling all regulatory requirements for effective leak detection.
  • Proven Disinfection Protocols: Disinfectants are injected into the system through designated ports, successfully passing biological safety tests including use of thermo-tolerant bacterial spores, ensuring comprehensive disinfection to meet official health and safety guidelines.
  • Valves of Versatility: Available in sizes ranging from DN100 to DN800 with customizable square valves, these are constructed from SUS304 and equipped with TFE/silicone seals. They are available for manual, electric, or pneumatic operation, with a finish that may be drawn or sandblasted according to preference. Their performance remains within the permissible leakage rate even after extensive use.
  • Durable Sealing Strips: Crafted from silicone capable of enduring extreme temperature fluctuations and resistant to chemical agents, these sealing strips come with the assurance of quality backed by CNAS and SGS certification.
  • Adaptable Safety Bags: Standard at 2m in length but customizable to meet various operational needs, these bags are made from PVC/polymer materials and are resilient against extreme temperatures and chemical reactions, ensuring reliable performance.

YOUTH's Innovative Airflow Configurations

Vertical Cleanroom BIBO Unit with Top-Down Airflow
Cleanroom BIBO Unit with
Top-Down Airflow
  • Vertical Airflow Design: The Cleanroom BIBO unit can be installed vertically, enabling airflow to move in either a top-down or a bottom-up direction.
Vertically Mounted Cleanroom BIBO Unit with Left-to-Right Airflow via Elbow Duct
Vertically Mounted
Cleanroom BIBO Unit with
Left-to-Right Airflow via Elbow Duct
  • Vertical with Elbow Duct: When vertically installed, the BIBO unit includes an elbow duct which redirects the airflow to move horizontally, either from left to right or right to left.
Horizontal Cleanroom BIBO Unit with Side-to-Side Airflow
Cleanroom BIBO Unit with
Side-to-Side Airflow
  • Horizontal Airflow Configuration: Designed for horizontal installation, the cleanroom BIBO unit facilitates airflow from left to right or right to left across the unit.

Streamlined Filter Section Definition

  • Filter Unit Count: The term ‘filter section’ pertains to the tally of individual filter units that the airstream traverses when it passes in and out of the filter section, considering the inlet’s cross-sectional area (for example, configurations may include 1, 2, or 3 units).
  • Assembly Capacity: A single filter section can accommodate an assembly of up to eight filter units, providing flexibility for various airflow requirements.

YOUTH BIBO Housing System's Specifications

  • High-Efficiency Filtration: Achieves a minimum of 99.97% particle capture rate for those sized at 0.3 micrometers.
  • Rigorous Air Tightness: Maintains air leakage from the housing at less than 0.25% of its net volume per hour, even under pressures of ±3500Pa.
  • Robust Pressure Tolerance: Designed to withstand a negative pressure of -2500Pa for an hour with no lasting structural changes, in compliance with exhaust device standards.
  • Leak Detection Capabilities: Offers the option for either manual or automated leak detection scanning methods.
  • Aerosol Concentration Consistency: Features nine strategically positioned measuring points near the upstream filter to ensure aerosol concentrations remain within ±20% of the mean.
  • Sterilization and Filter Replacement: Employs an in-situ gas sterilization process followed by a secure and efficient bag-in-bag-out filter change procedure.
  • Exceptional Corrosion Resistance: Constructed from 304 stainless steel, the housing is impervious to a wide range of chemical agents including disinfectants, cleaners, and various acidic and alkaline substances.


How does a BIBO system work?

It works by enclosing the contaminated filter within a secured bag within the housing unit, which is then safely removed, preventing the escape of particulates.

What does the ‘bag-in-bag-out’ process involve?

The process involves placing the contaminated filter into a bag (and sometimes a second outer bag), sealing it, and removing it from the housing without releasing contaminants.

What is the typical pressure tolerance of a BIBO system?

BIBO systems are constructed to withstand various pressure differentials, often up to ±2500pa or higher, depending on design specifications.

Is leak detection part of a BIBO system’s functionality?

Yes, YOUTH’s BIBO systems include manual or automatic leak detection capabilities to ensure filter integrity.

Can BIBO systems be integrated with existing HVAC systems?

BIBO units can often be integrated with HVAC systems; however, compatibility and integration requirements should be verified with the manufacturer.

What considerations should be made when choosing a BIBO system?

Considerations include the type of contaminants, required level of containment, air-flow design, and integration with existing systems.

BIBO System Related Name

Bag-in-Bag-out HEPA System:

This refers to an entire air filtration system that includes HEPA filters and operates on the BIBO principle. It ensures that all the components needed to filter out airborne particles and biological contaminants comply with the BIBO safety measures. The entire process of replacing the HEPA filter is safely contained to prevent contamination.

Bag-in-Bag-out Filter Port

The “bag in bag out port,” in the context of a Bag-in-Bag-out (BIBO) system, is a feature that allows the connection of a bag (used for safely removing and disposing of contaminated filters) to the filter housing or unit. The port is an integral part of the BIBO system’s design to ensure airtight and safe handling of hazardous materials.

Bag-in-Bag-out Filter Housing

It is the protective casing that holds a filter—usually a HEPA filter—while providing a secure method to replace it without exposing the environment or personnel to dangerous contaminants. The housing is designed so that when the filter needs to be changed, it can be placed into a bag while still within the housing. Once sealed, it can be safely removed, thereby minimizing the risk of exposure.

Bag-in-Bag-out HEPA Filter

The HEPA filter is used within a BIBO system. HEPA filters are high-efficiency particulate air filters that trap a high percentage of dust, pathogens, and contaminants. When it’s time to change out a HEPA filter in a sensitive environment, the BIBO technique is used. The used filter is enclosed in a bag before it is removed from its housing, and a new filter is placed without releasing contaminants into the air.

Bag-in-Bag-out Bag

The “bag” in the Bag-in-Bag-out (BIBO) process refers to the specialized containment bags used in the replacement procedure of filters in BIBO systems. These bags are made of durable materials designed to seal off and contain the hazardous particles collected by the filter. During a filter change, the contaminated filter is placed directly into this bag while still within the filter housing, thus minimizing the risk of exposure to dangerous materials.

Bag-in-Bag-out Unit

The term “unit” in the context of a BIBO system typically refers to the entire filtration unit, which includes the filter housing, the HEPA filters, and any other components necessary for the unit to function correctly in a contamination-controlled environment. The BIBO unit will have mechanisms in place to allow for the safe replacement of filters, ensuring that operators and the environment are not exposed to the contaminants trapped in the filters. The entire unit is engineered to provide high-efficiency particulate air filtration while also allowing for safe maintenance practices through the BIBO procedure.


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